Esthesioneuroblastoma – A Clinicopathological Study
نویسندگان
چکیده
Background: Esthesioneuroblastoma is a rare tumour accounting for only 3% of all intranasal tumors. Its proximity with important structures and aggressive behavior presents a diagnostic and therapeutic challenge. CT, MRI and histopathology forms the basic pillars of management. Methods: A prospective study was conducted between Feb 1998 to Feb 2004 in the Department of ENT, JNMC, AMU Aligarh. All the five patients taken up for study proved histopathologically to be cases of esthesioneuroblastoma. Results: Of the five patients, three presented with unilateral nasal obstruction (60%) and two with epistaxis (40%). Proptosis was present in one patient. Anosmia, headache and pain were other associated symptoms. Conclusions: hepatic and renal involvement occurs in patients suffering from dengue fever. Hence, multidisciplinary approach should be carried out while treating such patients.
منابع مشابه
Neck recurrence and mortality in esthesioneuroblastoma: Implications for management of the N0 neck.
OBJECTIVES/HYPOTHESIS To review the literature on neck recurrence in esthesioneuroblastoma. STUDY DESIGN PubMed database. METHODS A PubMed database search was performed using keywords "esthesioneuroblastoma," "olfactory neuroblastoma," and "esthesioneuroblastoma neck metastasis." Articles written in English with greater than 10 subjects that had data regarding the association of neck recurr...
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Distinction of high-grade esthesioneuroblastomas from other poorly differentiated tumors arising in the nasal cavity is an important diagnostic challenge because it determines patient management and prognosis. The human achaete-scute homologue (hASH1) gene is critical in olfactory neuronal differentiation and is expressed in immature olfactory cells; therefore, it could have potential use as a ...
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Background Esthesioneuroblastoma is an uncommon malignant neoplasm that arises from the olfactory neuroepithelium. In this article we report a case of esthesioneuroblastoma presenting concomitantly with a growth-hormone (GH)-secreting pituitary macroadenoma. Results A 52 year old woman underwent surgery for suspected nasal polyps. Intralesional debulking of an intranasal tumor disclosed a low-g...
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Metastasis to the breast from an extramammary malignant neoplasm, including esthesioneuroblastoma, is uncommon. The present study describes a rare case of sinonasal esthesioneuroblastoma, Hyams' histologic grade 2, Kadish's stage C, T4N0M0, in a 30-year-old female. The patient underwent a radical ethmoidectomy with external beam radiotherapy, followed by chemotherapy including five cycles of ci...
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